Search on:
BECLIN 1 PROTEIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Beclin-1
Descriptor
Spanish
:
Beclina-1
Descriptor
Portuguese
:
Beclina-1
Synonyms
English
:
ATG-6 Protein
ATG6 Protein
Beclin-1 Protein
Beclin1
Coiled-coil Myosin-like Bcl2-interacting Protein
GT197 Protein
ATG 6 Protein
Beclin 1
Beclin 1 Protein
Coiled coil Myosin like Bcl2 interacting Protein
Tree Number:
D12.644.360.075.335
D12.776.094.500
D12.776.476.075.335
Definition
English
:
An
autophagy
related protein which functions as a core subunit of
PHOSPHATIDYLINOSITOL 3-KINASE
MULTIPROTEIN COMPLEXES
. It mediates the formation of phosphatidylinositol 3-phosphate and functions in
AUTOPHAGY
, where it is required for maturation of the
AUTOPHAGOSOME
. It also functions in
ENDOCYTOSIS
and
CYTOKINESIS
as part of a separate complex.
Beclin-1
associates with
INTRACELLULAR MEMBRANES
and interacts with the
PROTO-ONCOGENE PROTEINS C-BCL-2
and
BCL-X PROTEIN.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56546
Unique Identifier:
D000071186
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS